Atrial Giant Cell Myocarditis

Atrial Giant Cell Myocarditis: A Distinctive Clinicopathologic Entity Running title: Larsen et al.; Atrial giant cell myocarditis

Atrial Giant Cell Myocarditis : A Distinctive Clinicopathologic Entity Running title

De De Dep pa part rtme ment nt nt of Pa Path thol log ogy, y, Uni nive v rs sity y of f Arizo zona na, T T Tucs son on, , AZ; ; Ad Addr dres ess s fo for r Co Corr rres espo pond nden ence ce: : Abstract: Background—Giant cell myocarditis (GCM) typically causes fulminant heart failure,

Atrial giant cell myocarditis: a distinctive clinicopathologic entity.

BACKGROUND Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinical features and follows a more benign course than ventricular GCM. METHODS A...

Giant Cell Myocarditis

One of the possible causes of dilated cardiomyopathy is considered to be a sequel to myocarditis. Two mechanisms have been proposed in the process of progression of myocarditis into dilated cardiomyopathy: one is a persistent viral infection, and the other is an autoimmune myocardial injury. To clarify the possible part played by the autoimmune mechanism in the process, using an animal model, w...

Giant Cell Versus Lymphocytic Myocarditis

Background. Giant cell myocarditis has rarely been diagnosed premortem, and little is known about its natural history. In addition, no comparative studies with lymphocytic myocarditis exist. Methods and Results. The clinical features, serial change in left ventricular fraction (LVEF), and outcomes of all patients with histologically verified myocarditis were retrospectively evaluated. Ten patie...